Tobey Maguire

• Spider-Man / Peter Parker

Kirsten Dunst

• Mary Jane Watson

James Franco

• Harry Osborn

Alfred Molina

• Doc Ock / Otto Octavius

Rosemary Harris

• May Parker

J.K. Simmons

• J. Jonah Jameson

Donna Murphy

• Rosalie Octavius

Daniel Gillies

• John Jameson

Dylan Baker

• Dr. Curt Connors

Bill Nunn

• Joseph 'Robbie' Robertson

Vanessa Ferlito

• Louise

Aasif Mandvi

• Mr. Aziz

Willem Dafoe

• Green Goblin / Norman Osborn

Cliff Robertson

• Ben Parker

Ted Raimi

• Hoffman

Elizabeth Banks

• Miss Brant

Bruce Campbell

• Snooty Usher

Gregg Edelman

• Dr. Davis

Ilya Baskin

• Mr. Ditkovitch

Mageina Tovah

• Ursula

Daniel Dae Kim

• Raymond

Hal Sparks

• Elevator Passenger

Joel McHale

• Mr. Jacks

Stan Lee

• Man Dodging Debris

• Actor

Kelly Connell

• Dr. Isaacs

Brent Briscoe

• Garbage Man

Emily Deschanel

• Receptionist

Jason Fiore-Ortiz

• Henry Jackson

Scott Spiegel

• Man on Balcony

Andy Bale

• OsCorp Executive

Christine Estabrook

• Mrs. Jameson

Molly Cheek

• Society Woman

John Paxton

• Houseman

Joy Bryant

• Woman at Web

Joanne Baron

• Skeptical Scientist

Peter McRobbie

• OsCorp Representative

Timothy Jerome

• Injured Scientist

Taylor Gilbert

• Mrs. Watson

Peter Vouras

• Stage Manager

Donnell Rawlings

• Pizza "Heist" Witness

Zachry Rogers

• Boy saved by Spider-Man

Ella Rogers

• Girl saved by Spider-Man

Louis Lombardi

• Poker Player

Marc John Jefferies

• Amazed Kid

Roshon Fegan

• Amazed Kid

Brendan Patrick Connor

• Theater Traffic Cop

Reed Diamond

• 'Algernon'

Dan Callahan

• 'Jack'

Elyse Dinh

• Violinist

John Landis

• Doctor

Tim Storms

• Chainsaw Doctor

Susie Park

• Clawing Nurse

Patricia M. Peters

• Screaming Nurse

Michael Edward Thomas

• Man at Fire

Anne Betancourt

• Woman at Fire

Venus Lam

• Child in Burning Building

Bill E. Rogers

• Fireman

Joe Virzi

• Fireman

Tom Carey

• Train Conductor

Jopaul Van Epp

• Boy with Mask

Weston Epp

• Boy with Mask

Peter Allas

• Train Passenger

Brianna Brown

• Train Passenger

Bill Calvert

• Train Passenger

Tony Campisi

• Train Passenger

Joey Diaz

• Train Passenger

Chloe Dykstra

• Train Passenger

Simone Gordon

• Train Passenger

Dan Hicks

• Train Passenger

Julia Max

• Train Passenger

Savannah Pope

• Train Passenger

Timothy Patrick Quill

• Train Passenger

Jill Sayre

• Train Passenger

Rickey G. Williams

• Train Passenger

Michael Arthur

• NYPD Officer (uncredited)

Frank Bonsangue

• Pizza Man (uncredited)

Cindy Cheung

• Chinese Daughter (uncredited)

Phil LaMarr

• Train Passenger (uncredited)

Andre M. Johnson

• Fireman 2 (uncredited)

Peter Cincotti

• Piano Player in Planetarium (uncredited)

Peyton List

• Little Girl Playing on Steps (uncredited)

Spencer List

• Little Boy Playing on Steps (uncredited)

Troy Metcalf

• Blue Collar Guy (uncredited)

Scott Ross

• Pedestrian (uncredited)

Bonnie Somerville

• Screaming Woman (uncredited)

Wesley Volcy

• Columbia University Student (uncredited)

Lou Volpe

• Man at Web (uncredited)

Garrett Warren

• Bearded Doctor (uncredited)

Joseph M. Caracciolo

• Priest at Mary Jane's Wedding (uncredited)

David Boston

• Pedestrian (uncredited)

Sho Brown

• Passenger (uncredited)

Sal Ardisi

• Parent (uncredited)

Edward Johnson

• Planetarium (uncredited)

Grant Curtis

• Hot Dog Vendor (uncredited)

Vince Cupone

• Victim (uncredited)

William E. Corcoran

• Stock Broker (uncredited)

Mohammed Hassan

• Middle Eastern Taxi Driver (uncredited)

Rachel Lehrer

• Hot Girl (uncredited)

Gene LeBell

• Train Passenger (uncredited)

Lorelei Llee

• Bank Employee (uncredited)

Joseph Nelson

• Extra (uncredited)

Claudia Katz Minnick

• Robbie's Assistant (uncredited)

Ronn Ozuk

• Cop (uncredited)

Denney Pierce

• Train Passenger (uncredited)

Carla Rhodes

• Phone Booth Girl (uncredited)

Randy Reinholz

• Train Passenger (uncredited)

Rachelle Roderick

• Jane, Engineer (uncredited)

Angel Katherine Taormina

• Female Onlooker on Street (uncredited)

Douglas Swander

• Train Passenger (uncredited)

Jimmy Star

• Reporter (uncredited)

Jack Wetherall

• Train Passenger (uncredited)

Ken Wharton

• Uptight Businessman (uncredited)

Henry Truong

• Doc Ock Lab Assistant #2 (uncredited)

Al Collado

• Cab Driver (uncredited)

Lee Cogburn

• Train Passenger (uncredited)

Sam Raimi

• University Student with Bag (uncredited)

John Cameron

• Man Buying 'Spider-Man No More' Newspaper (uncredited)

Joseph M. Caracciolo Jr.

Alvin Sargent

Jay Hart

Laura Ziskin

Lorne Orleans

Stan Lee

• Actor

Kevin Feige

Avi Arad

Bill Pope

Bob Murawski

Danny Elfman

Sam Raimi

Dianne Crittenden

Neil Spisak

James Acheson

Cinzia Angelini

Alexa Sheehan

Billy Taylor

Gary Archer

Miles Millar

Michael Chabon

Alfred Gough

John Dillon

Grant Curtis

Steve Bartek

Gary Jones

Armen Ksajikian

Lisa Hoyle

Steve Ditko

Bill Abbott

J.C. Brotherhood

Matt Blades

Jeff Knipp

Gershon Hinkson

Thomas P. Wilkins

Scott P. Murphy

Dan Bradley

Thomas Valentine

Steve Saklad

Trish Almeida

Tricia Heine

Eric Heffron

Hank Amos

Trudy Ramirez

Eran Barnea

Brinton Bryan

Lisa Hannan

Chris Haynes

Larry Hopkins

David Campbell

Joseph M. Caracciolo

Michael V. Nicolo

Jason Hamer

Timothy Healy

J. Bryan Holloway

Wayne Shepherd

Cosmas A. Demetriou

Jason Bartolone

Paulette Fox

Wayne Baker

Anita Lausevic

Tim Arasheben

Kenji Luster

John Bramley

Jim Ondrejko

Theresa Greene

James Carson

Bill Garvey

C. Scott Baker

Jan O'Connell

Nour Dardari

Dan Harder

Susan Dukow

Raoul Bolognini

Sean Valla

Paul N.J. Ottosson

Timothy Michael Cairns

Cottalango Loorthu

Sandy O'Neill

Kelvin R. Trahan

Laura Berning

Dennis Sands

Greg Anderson

Douglas Cannon

Robert Barnett

Todd Bassman

Carlye Archibeque

Michael K. Reynolds

William Ramirez Jr.

Don Poole

Richard Baratta

Bob Finley III

Alicia Kalvin

Al Cerullo

Gretchen Gain

Michael Kall

Danny Cangemi

John Orlebeck

Julie Adrianson-Neary

Clare Hallworth

Daniel Eaton

Hank Amos

Christopher Wolf

David J. Grant

Joseph Geisinger

John M. Chalfant

Joseph V. Cicio

David Irvine

Steven Clawson

Tamara Bally

Paul N.J. Ottosson

Vinson Jae

Debbie Lucas

Cyril O'Neil

Heather Sharpe

Jody Fedele

Frank Dorowsky

Julie Hewett

Steve Bartek

Carey Smith

Jim Passon

Sidney Brisco

Scott G.G. Haller

Noriko Watanabe

Cheryl Rusa

Chad Stahelski

Chris O'Hara

Diana R. Lupo

Jenifer Bonisteel

Kelly R. Borisy

Sara Auhagen

Dion Lam

Ulrika Akander

Susan Dudeck

Colin Drobnis

Ivory Stanton

Jason Kay

Mary Jo 'MJ' McGrath

Peter Giliberti

Bob Mano

Ulrike Lamster

Daniel Pershing

Kevin Flatow

Vincent Truitner

Elisa Marsh

Christian Ristow

Adam Austin

Kyle Cooper

Bac DeLorme

Mo Henry

George Doering

Susan Dudeck

Scott Getzinger

Egan Gauntt

Bob Moore Jr.

Joanne Lamstein

Sean Landeros

Doug Harlocker

Alison Fisher

Ulrika Akander

Douglas J. Schulman

Stan Lee

• Actor

Todd Harris

Tad Griffith

John Dykstra

Jill Brown

Kevin Flynn

Santena Jenaris King Clough

Marilyn DeJesus

Lorraine Crossman

James Bearb

Braden Belmonte

Anthony Harris

Dan Bradley

Anthony B. LaMolinara

Luis Grané

Jason Rody

Mark McDevitt

Michael Backes

François Audouy

Howard London

H. Barclay Aaris

Jean Chien

Andy Ryan

Jerry Bingham

Tony Hobbs

Judy Pursley

Alexandra K. Browne

Michael Scarola

Christopher Flick

Chris Daniels

Anette Haellmigk

James Boniece

Shannon Gaulding

Carlo Pratto

Alethea McElroy

Alex Borys

Angela Athayde

Chris John Jones

Tricia Linklater

Joseph M. Horrigan

Jeff Shiffman

Thomas Moffitt

Lynda Kyle Walker

Patti Gannon

Dave Ardinger

Aaron Scully

Trilochan Naik

Basia Emano

Nancy Parker

Steve Robertson

Michael Healey

Tina Dowd

Giselle Brewton

Pete Anthony

Kathryn Malone

Kristen Branan

Grant Anderson

Kirk Bloomberg

Scott Stokdyk

John Dykstra

Kevin O'Connell

Greg P. Russell

John Frazier

Jeffrey J. Haboush

Joseph S. Alfieri

Brad Martin

Brad Martin

Robert Alonzo

Billy Bryan

Joseph Keyes

Rocky Gehr